CompletedPhase 2/3

Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain

24 participantsStarted 2017-01-02

Plain-language summary

This is a clinical trial that intend to determine the effects of S-ketamine on event-related potentials associated with semantic affective pain-processing

Who can participate

Age range18 Years – 40 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * male healthy subjects with higher education level Exclusion Criteria: * do not understand Portuguese language * obese patients (BMI \> 27 kg/m2) * use of NSAID, steroids, analgesics, anticonvulsant drugs, as well as alpha and beta-blockers * score ≥ 13 on Beck II Questionnaire * sleep deprivation in the night before evaluation

What they're measuring

AUC of the grand averaged mean differences between ERPs elicited by target and non-target words

Timeframe: up to 60 min

Trial details

NCT IDNCT03915938

SponsorHospital de Clinicas de Porto Alegre

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-11-30

View on ClinicalTrials.gov More Acute Pain trials