Thigh Cuffs to Prevent the Deconditioning Induced by 5 Days of Dry Immersion

Inclusion Criteria: * Healthy male volunteer (see below the description of medical tests and laboratory analysis performed at the selection visit), * Age 20 to 45, * No overweight nor excessive thinness with BMI (weight Kg/ height m2) between 20 and 26, * Height between 158 and 185 cm, * No personal nor family past record of chronic or acute disease or psychological disturbances which could affect the physiological data and/or create a risk for the subject during the experiment, * Fitness level assessment: * if age \< 35 years: 35 ml/min/kg \< VO2max \< 60ml/min/kg * if age \> 35 years: 30 ml/min/kg \< VO2max \< 60ml/min/kg * Walking between 7000 - 8000 steps/day, * Active and free from any orthopedic (in particular no vertebral fracture, scoliosis or herniated disc) musculoskeletal and cardiovascular disorders, * Non smokers, * No alcohol, no drug dependence and no medical treatment, * No antibiotic treatment in the 2 previous months before the beginning of the study, * Covered by a Social Security system, * Have signed the information consent, * Free of any engagement during the study. Exclusion Criteria: * \- Past record of orthostatic intolerance, * Cardiac rhythm disorders, * Chronic back pains, * Vertebral fracture, scoliosis or herniated disc, * Glaucoma, * HTA, * History of migraines, * History of hiatus hernia or gastro-esophageal reflux, * History of thyroid dysfunction, renal stones, diabetes, * History of head trauma, * Past records of thrombophlebitis, fa…