CompletedNot Applicable

Facilitating Optimal Routines in Aging

United States105 participantsStarted 2019-07-31

Plain-language summary

Loss of cognitive abilities leading to Alzheimer's disease is progressive and destructive, leaving older adults disabled and unable to recall their past. The number of older adults with Alzheimer's disease is expected to triple by the year 2050, yet little research examines amyloid beta deposition, executive function, and progression of disability. This study will test the influence of a novel and promising non-pharmacological intervention, Strategy Training, on the progression of disability in a sample of 150 older adults with Mild Cognitive Impairment who have the option to complete a Positron Emission Tomography (PET) Imaging with Pittsburgh Compound B (PiB).

Who can participate

Age range60 Years

SexALL

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Inclusion Criteria: * Diagnosis of Mild Cognitive Impairment * Acknowledge difficulty with a daily activity * Community dwelling Exclusion Criteria: * Pregnant * Central Nervous System disorder (other than MCI) * Substance disorder in past 5 years * Lifetime history of bipolar disorder, schizophrenia, or deemed unsafe to proceed in the study (e.g., untreated Major Depressive Disorder) * Severe medical condition that limits engagement in daily activities

What they're measuring

Change in disability

Timeframe: Baseline to Month 12

Trial details

NCT IDNCT03913637

SponsorUniversity of Pittsburgh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11-30

View on ClinicalTrials.gov More Mild Cognitive Impairment trials