Evaluation of the Clinical Performance of the Quantra System With the QStat Cartridge

Inclusion Criteria: * Subject is ≥ 18 years of age * Subject has one of the following conditions and is a candidate for a ROTEM test to be performed to access coagulopathy: trauma patient; patient with OB hemorrhage. * For trauma patients; subject must be experiencing major trauma (preferably requiring the highest level of team activation) with active bleeding or deemed at high risk of significant bleeding according to mechanism of injury. * For subjects experiencing OB hemorrhage, one of the following conditions must be met (to be confirmed): * Estimated blood loss during vaginal delivery is greater than 1000 mL * Estimated blood loss during cesarean delivery is greater than 1500 mL * Placental abruption with hemorrhage of any quantity blood loss * Clinically suspected disseminated intravascular coagulation (DIC) * Is under consideration for administration of tranexamic acid (TXA) for treatment of hemorrhage. * Subject is willing to participate, and is willing to consent (either prospectively or by deferred consent) Exclusion Criteria: * Subject is younger than 18 years of age * Subject is known to have received antifibrinolytic therapy immediately prior to presentation to trauma unit or during labor just prior to OB hemorrhage. * Subject is unable to provide written informed consent (either prior to performing any study related procedures or by deferred consent) * Subject is currently enrolled in a distinct study that might confound the results …