Aerobic Exercise Program Followed by Cold Water Immersion: Effects on Arthritis Patients Arterial… (NCT03911830) | Clinical Trial Compass
CompletedNot Applicable
Aerobic Exercise Program Followed by Cold Water Immersion: Effects on Arthritis Patients Arterial Stiffness
France18 participantsStarted 2017-11-11
Plain-language summary
The purpose of this study is to analyze the long-term effects of a physical exercise program on the cardiovascular system of people with Rheumatoid Arthritis (RA).
Indeed, it is recognized that RA patients have cardiovascular problems and that regular physical exercise (exercise training) may be beneficial for the disease complications, incluse the cardiovascular risk. Unfortunately, these patients do not exercise enough for fear of joint pain or for fear of deteriorating their general physical condition.
It is known that intermittent exercises, ie combining low and high intensity work phases, are particularly effective in the cardiovascular field. As it is possible that the high intensity phases be more difficult to sustain than the low intensity phases (joint pain and degradation of the inflammatory status), the investigators propose to study the effects of cold water immersion in the legs after performing this exercise, because the cold being recognized as limiting the pain and improving the inflammatory status.
Who can participate
Age range20 Years – 80 Years
SexALL
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Inclusion Criteria:
* Patient (male or female) between the ages of 20 and 80, diagnosed with rheumatoid arthritis without any other risk factor in relation to RA, and having a DAS-28 score between 2.6 and 6.
* Signature of informed consent
* Affiliation to a French social security scheme or beneficiary of such a scheme.
Exclusion Criteria:
* Unstabilized corticosteroids and / or\> 10 mg prednisone / day;
* Unstabilized hypertension;
* Pregnant women;
* Alteration of higher functions making comprehension and adherence to a conditioning program impossible (mini mental test \<24); Patient who has performed intense physical exercise / physiotherapy within the previous 24 hours the interventions planned in this project;
* Contraindication to immersion in cold water (a dermatological factor and / or vascular or respiratory cardiac dysfunction and / or cold intolerance syndrome and / or syndrome such as Raynaud's Syndrome);
* Inability to perform physical exercise, regardless of its origin (neurological, central or peripheral, cardiovascular or respiratory or musculoskeletal);
* Legal incapacity or limited legal capacity;
* Subject unlikely to cooperate with the study and / or weak cooperation anticipated by the investigator;
* Subject without health insurance;
* Subject being in the exclusion period of another study or provided for by the "National Volunteer File".
What they're measuring
1
Pressure wave analysis
Timeframe: Week 6
2
Assessment of central arterial compliance
Timeframe: Week 6
Trial details
NCT IDNCT03911830
SponsorCentre Hospitalier Universitaire de Besancon