SuspendedNot Applicable

Neuromuscular Adaptations After Training in the Muscle Belly of Triceps Surae

Stopped: Dr. Karenina has to change for another projetct due to Covid pandemic.

Brazil60 participantsStarted 2019-04-15

Plain-language summary

This study aims to evaluate on an acute session of the central and peripheral contributions of electrical stimulation on the muscle belly of the triceps surae, electrical stimulation of the tibial nerve and voluntary exercise of the triceps surae muscle, and identify responders individuals and non-responders to stimulation of the tibial nerve. Another objective of the study is to compare the effects of conventional electrical stimulation applied to the sciatic triceps muscle, tibial nerve stimulation and voluntary exercise after eight weeks of training in healthy individuals.

Who can participate

Age range

18 Years – 30 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Classified as physically active according to the INTERNATIONAL QUESTIONNAIRE OF PHYSICAL ACTIVITY, * To practice only recreational physical activity, * Achieve minimum torque of 30% of the (maximal voluntary isometric contraction during conventional NMES * Be at least 3 months without practicing strength training. Exclusion Criteria: * Present some type of skeletal muscle dysfunction that may interfere with the tests, * Present intolerance to NMES in the muscular or tibial nerve, Make use of analgesics, antidepressants, tranquillizers or other agents of central action * To present cardiovascular or peripheral vascular problems, chronic diseases, neurological or muscular affections that will undermine the complete execution of the study design by the volunteer.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change from Baseline Central contribution (H reflex) after 15 minutes of acute session of electrical stimulation.

Timeframe: Baseline and after 15 minutes of electrical stimulation in the acute session.

Change from Baseline Central contribution (H reflex) after 8 weeks of training with electrical stimulation.

Timeframe: Baseline and after 8 weeks of training with electrical stimulation.

Change from Baseline Peripheral contribution (M wave) after 15 minutes of acute session of electrical stimulation

Timeframe: Baseline and after 15 minutes of electrical stimulation in the acute session

Change from Baseline Peripheral contribution (M wave) after 8 weeks of traning with electrical atimulation

Timeframe: Baseline and after 8 weeks of training with electrical stimulation

Change from Baseline Voluntary torque after 8 weeks of training with electrical stimulation

Timeframe: Baseline and after 8 weeks of training with electrical stimulation

Change from Baseline Electromyographic signals after 8 weeks of training with electrical stimulation

Timeframe: Baseline and after 8 weeks of training with electrical stimulation

Trial details

NCT IDNCT03905772

SponsorUniversity of Brasilia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-05-01

View on ClinicalTrials.gov More Electrical Stimulation trials