CompletedPhase 4

Lidocaine Infusion for Pain Relief in Children Scheduled for Tonsillectomy and Adenoidectomy

United States70 participantsStarted 2019-05-07

Plain-language summary

Lidocaine is widely available and is a very commonly used local anesthetic. When administered intravenously, lidocaine infusions have anti-inflammatory effects and have significantly decreased the reliance on opioid use for adequate pain management in adult abdominal and spine surgeries. A major advantage of lidocaine infusion is that it is not associated with a significant side effect profile.The role of lidocaine in pediatric acute perioperative pain remains limited.

Who can participate

Age range4 Years – 10 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- scheduled tonsillectomy and adenoidectomy with or without myringotomy/PE tubes at Hasbro Children's Hospital Exclusion Criteria: * history of allergies to local anesthetics * physical or developmental delays * psychiatric illness * current use of sedative or anticonvulsive medications * use of premedication (oral/nasal) * pre-existing cardiovascular, renal, or hepatic disease * pre-existing cerebral or neuromuscular disease * patient with personal or family history of malignant hyperthermia * recent history of upper respiratory infection within last 7 days * regular use of analgesic medications

What they're measuring

Change in Pain Scores

Timeframe: 15 minute intervals in postanesthesia care unit; up to 120 minutes following surgery.

Trial details

NCT IDNCT03902314

SponsorRhode Island Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-06

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