CompletedPhase 4

Ideal Steroids for Asthma Treatment in the PICU

United States92 participantsStarted 2019-04-21

Plain-language summary

Determine if differences in (1) pediatric intensive care unit length of stay, (2) continuous nebulized albuterol duration, and (3) a composite outcome of advanced asthma therapy incidence including use of non-invasive ventilation (NIV), terbutaline, inhaled helium and mechanical ventilation between cohorts of children admitted with status asthmaticus to the PICU treated with either IV dexamethasone (DM) or methylprednisolone (MP).

Who can participate

Age range5 Years – 17 Years

SexALL

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Inclusion Criteria: * Inclusion criteria are children 5 to 17 years of age with primary admission diagnoses of acute asthma exacerbation or status asthmaticus admitted to the PICU Exclusion Criteria: * children with existing tracheostomy, cystic fibrosis, and pulmonary hypertension

What they're measuring

Length of Stay

Timeframe: From enrollment through hospital discharge, up to 1 week

Trial details

NCT IDNCT03900624

SponsorJohns Hopkins All Children's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-31

Results submitted2022-08-04

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