CompletedNot Applicable

Practical Approaches for Interrupting Prolonged Sitting to Improve Postprandial Glucose and Protein Metabolism

Canada14 participantsStarted 2018-10-19

Plain-language summary

The present study will determine the impact of interrupting prolonged sitting with short, 2-minute walks or body-weight squats on: i) postprandial glycemia and insulinemia, and; ii) postprandial utilization of dietary amino acids. We hypothesize that postprandial glycemia and insulinemia will be similarly improved by interrupting prolonged sitting with short walks or body-weight squats, whereas postprandial utilization of dietary amino acids will only be improved by interrupting prolonged sitting with body-weight squats.

Who can participate

Age range18 Years – 35 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Men and women between 18-35 yr * Recreationally active (≤ 150 minutes of moderate-intensity physical activity per week and no more than 3 days/week of exercise) * VO2peak considered "good" or below based on ACSM age and sex normative values * Experiencing regular menstrual periods and not taking hormonal oral contraceptives (females only) Exclusion Criteria: * Inability to perform physical activity as determined by the PAR-Q * Inability to adhere to protocol guidelines (e.g. alcohol, standardized diet) * Physical limitations for walking or repeatedly rising from a chair * Regular tobacco use * Illicit drug use (e.g. growth hormone, testosterone) * Hormonal oral contraceptive use (females only) * Diagnosed medical condition under the care of a physician (e.g. type 2 diabetes)

What they're measuring

Postprandial insulin area under the curve (AUC) to breakfast and lunch

Timeframe: 3 hours postprandial

Trial details

NCT IDNCT03896828

SponsorUniversity of Toronto

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-12-01