Recovery Initiation and Management After Overdose (RIMO) Experiment (NCT03895827) | Clinical Trial Compass
CompletedNot Applicable
Recovery Initiation and Management After Overdose (RIMO) Experiment
United States251 participantsStarted 2022-04-01
Plain-language summary
This study targets individuals in Chicago who have received naloxone administered by first responders within the past week to reverse an overdose, but who have not entered into MAT. Study participants will be recruited through partnerships with the Chicago Fire Department (CFD) and/or Police Department (CPD); first responders will be trained to seek consent from individuals who are alert and oriented after receiving naloxone for future contacts by research staff as part of the naloxone standard protocol. Those who consent will be contacted and screened for study eligibility ideally within one week of naloxone administration; eligible participants will be randomly assigned either to the control group, i.e., referral to MAT as usual, or to Recovery Initiation and Management after Overdose (RIMO), an assertive linkage and recovery support intervention. This intervention builds on an evidence-based intervention for treatment linkage, monitoring, and recovery support evaluated in 3 prior clinical trials by the study team.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* experienced an opioid overdose reversed with naloxone administered by first responders on a participating team within the past week
* not in treatment during the past 30 days
* screen positive for an OUD
Exclusion Criteria:
* under age 18
* unable to speak and understand English
* not residing in Chicago
* cognitively unable to provide informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial looked at how quickly people started medication-assisted treatment after an overdose and how long they stayed on it — can you help me understand what those outcomes might mean for my own situation and whether starting medication right after an overdose is something worth considering for me?
2Since this study is already completed, have the results been published, and if so, what did they show about whether people who started MAT sooner after an overdose were more likely to stick with it long-term?
3The trial focused specifically on people with opioid use disorder recovering after an overdose — does my current history and situation match the kind of patients who were studied here, and would those findings actually be relevant to my care?
4This trial is listed as Phase NA, which often means it was more of a program or systems study than a traditional drug trial — so does it tell us anything about a specific medication being better, or is it more about the timing and process of getting people into treatment?
5Are there standard-of-care options for starting medication-assisted treatment right now that my care team would recommend, and how does what was studied in this trial compare to what I could access today without enrolling in any research?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.