The Effect of Loading Dose of Magnesium Sulfate on Uterine, Umbilical, and Fetal Middle Cerebral Arteries Doppler, Biophysical Profile, CTG, Maternal Vital Signs in Women With Severe Preeclampsia

Inclusion Criteria: * Singleton pregnancy. * Primigravida or Multigravida. * Pregnant females ≥ 37 weeks of gestation. * Diagnosed as severe preeclampsia by the following criteria: * Sustained systolic blood pressure of ≥160 mmHg or a sustained diastolic blood pressure of ≥ 110 mmHg. * Proteinuria measured as +1 or more by dipstick or 24 hours urine collection with proteinuria ≥ 0.3 grams. * Oliguria or creatinine \> 1.1 mg%. * Laboratory findings characteristic of HELLP syndrome. * Symptoms suggestive of severe preeclampsia ; severe headache, blurring of vision, epigastric pain. Exclusion Criteria: * Multifetal pregnancy. * History of epilepsy. * Patients with diabetes. * Patients with renal disease. * Fetuses with congenital anomalies. * Patients receiving anticoagulants e.g. heparin (unfractionated or low molecular weight). * Patients with severe IUGR. * Patients with accidental hemorrhage.