UnknownNot Applicable

Topography Versus Non-Topography-Guided PRK With CXL in Keratoconus

Iran38 participantsStarted 2017-03-30

Plain-language summary

To our knowledge, this study is one of the first to compare the visual results of non-topography-guided and topography-guided photorefractive keratectomy (PRK) applying sequential and simultaneous corneal cross-linking (CXL) treatment for keratoconus. Considering recent advances in cross-linking and imaging in keratoconus, the outcomes of this study can lead us to several non-invasive algorithm management options.

Who can participate

Age range34 Years – 41 Years

SexALL

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Inclusion criteria * age 34 (range from 34 to 41) * stable corneal topography and refraction for at least six months * estimated residual bed thickness of \>410 µm Exclusion * presence of macular or retinal disease, * dry eye * history of recurrent corneal erosions * anterior segment abnormalities * unstable refractive error * post-surgically residual stromal bed thickness of under 350 mm * autoimmune disease * collagen vascular disease * immunosuppressive therapy or current use of systemic corticosteroids * diabetes mellitus * pregnancy * lactation

What they're measuring

visual acuity

Timeframe: 3 months

Trial details

NCT IDNCT03890718

SponsorShahid Beheshti University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-09-30

View on ClinicalTrials.gov More Keratoconus trials