UnknownPhase 1

Treatment of Freckles by Intradermal Tranexamic Acid Versus Q Switched KTP Laser.

Egypt30 participantsStarted 2019-01-15

Plain-language summary

Comparative split face study in which 30 patients with freckles are recruited.One side of the face will be treated with Q Switched (QS)KTP 532nm, and the other side will be treated with intradermal tranexamic acid (TXA).

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Both genders * Age group \> 18years old. Exclusion Criteria: * Pregnant and lactating females. * Keloid and scarring tendancy * Usage of invasive or semi invasive procedures for treatment of freckles such as chemical peeling , dermaroller..etc. 2 months prior to the study. * Oral Isotretinoin 6 months prior to the study. * Active herpetic lesions. * Any concurrent active skin disease within the treated area. * Photosensitive skin conditions such as systemic lupus erythematous. * History of delayed wound healing. * Bleeding diathesis. * Medical conditions such as autoimmune diseases.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pigmentation and severity index by clinical evaluation

Timeframe: 6 months to 1 year

Melanin Index change by spectrophotometer

Timeframe: 6 months to 1 year

Blinded observers' evaluation

Timeframe: 6 months to 1 year

Patient satisfaction rate

Timeframe: 6 months to 1 year

Trial details

NCT IDNCT03885895

SponsorKasr El Aini Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-08

Contact for this trial

Samar Tuqan

01003133495 samartuqan@gmail.com

View on ClinicalTrials.gov More Therapeutic Efficacy trials

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.