CompletedNot Applicable

Complication and Lung Function Impairment Prediction Using Perfusion and CT Air Trapping

France160 participantsStarted 2020-09-21

Plain-language summary

The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for predicting post-operative forced expiratory volume in 1 second (FEV1) values for lung resection candidates; this new model will be based on data derived from a thoracic CT scan with injection of contrast media.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient diagnosed with non-small cell lung cancer * Indication for pulmonary excision surgery * Patient requiring a more recent pre-surgical computed tomography scan (CT scan) * The patient has been correctly informed about the study and has signed the consent form * The patient is affiliated with or a beneficiary of the French single-payer social security programme (national health insurance) Exclusion Criteria: * Patient in an exclusion period determined by another protocol * Participation in another study that may affect the results of the present study (anti-cancer treatment studies are allowed) * Patient under legal or judicial protection * Contraindication to surgery or iodine injection * Pregnant or lactating women

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Forced expiratory volume in 1 second (FEV1) from spirometry

Timeframe: 6 months

Correlation between predicted and real values for post-surgical FEV1

Timeframe: 6 months

Trial details

NCT IDNCT03885765

SponsorUniversity Hospital, Montpellier

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-04-18

View on ClinicalTrials.gov More Non-small Cell Lung Cancer trials