TerminatedPhase 4

Steroid Sensitive Nephrotic Syndrome in Children

Stopped: The study was terminated at all but one site because of the pandemic

United States, China34 participantsStarted 2019-08-06

Plain-language summary

Idiopathic nephrotic syndrome (INS) is one of the most common glomerular pathologies in children and corticosteroid therapy is its most effective treatment. The total duration of treatment ranges anywhere from two to six months, generally about 3 months. The main objective of our study is to test the feasibility of a shorter total duration (two months) of corticosteroid therapy in patients who show a quicker treatment response to the initial treatment.

Who can participate

Age range1 Year – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 1 to \<19 years * Newly diagnosed INS * Patient in remission with steroids * Written informed consent/Assent for the study OR as required by the local IRB Exclusion Criteria: * Age \< 1 year or ≥ 19 years * Uncertainty about patient/parent adherence. * Abnormal serum creatinine for patient age * Steroid resistant nephrotic syndrome * Any co-morbid condition that might require modification in treatment with steroids.

What they're measuring

Time to first relapse.

Timeframe: 60-64 weeks

Trial details

NCT IDNCT03878914

SponsorWayne State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-10-31

View on ClinicalTrials.gov More Nephrotic Syndrome in Children trials