CompletedNot Applicable

The Effect of Oxytocin on the Consolidation of Trauma-Associated Memories

Germany217 participantsStarted 2019-03-06

Plain-language summary

The purpose of the study is to examine whether oxytocin and certain polygenic risk scores affect the development of intrusive memories, a cardinal symptom of PTSD.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion Criteria: * healthy female volunteers * German on a native level Exclusion Criteria: * former or present disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) * any physical illnesses * any medication intake (except oral contraceptive) * history of traumatic experience, e.g. history of sexual abuse or rape * pregnancy or lactation period * follicular phase of menstrual cycle for all women not using oral contraceptives

What they're measuring

Change of Intrusive Memories in the following four days after the intervention

Timeframe: four consecutive days

Trial details

NCT IDNCT03875391

SponsorCharite University, Berlin, Germany

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-12-31

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