CompletedNot Applicable

Neuro-ophthalmology and Autoimmune Encephalitis (NODE)

France2 participantsStarted 2020-01-22

Plain-language summary

Autoimmune encephalitis represents a group of rare and heterogeneous neurological disorders. Pathophysiological mechanisms in these diseases are still unknown. Recently, oculomotor and neurovisual disorders have been described. Cerebral areas and neuronal networks associated with these abnormalities are well described. The investigator proposes to study and describe such neuro-ophthalmological disorders in a prospective cohort of patients with a autoimmune encephalitis, to better understand the pathophysiological basis of this neurological condition.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of autoimmune encephalitis * With or without pathological antibody * Aged from 18 to 70 years old * Able to understand the aims and methods of this project * Non opposed to the participation of this study Exclusion Criteria: * Other neurological, psychiatric or systemic conditions, which could induce neuro-ophthalmological signs Cognitive impairment, which is not linked to autoimmune encephalitis * Ophthalmological condition, which could modify the interpretation of neuro-ophthalmological data Inability to remain seated * Pregnancy or breast feeding * Adults under guardianship

What they're measuring

Percentage of patients presenting a neuro-ophthalmological abnormality.

Timeframe: Day 0

Percentage of patients presenting neuro-ophthalmological abnormality.

Timeframe: At 6 months if an abnormality is found

Trial details

NCT IDNCT03872284

SponsorHospices Civils de Lyon

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-02-26

View on ClinicalTrials.gov More Autoimmune Encephalitis trials