Anterior talofibular ligament is the most injured ligament in ankle sprain. Investigators will include ankle sprain patients who have ankle pain or instability more than 3 months. Ultrasonography will be done for confirm ligament injury. Participants will be randomized into two groups. Participants in dextrose injection group will accept dextrose 15% injection to tendon and enthesis. In the other hand, subcutaneous sham injection to control group. Pain condition, stability test and function test, will be evaluated in 1 week, 4 weeks and 12 weeks after injection.
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Ankle pain
Timeframe: Change from baseline VAS at 1 week
Ankle pain
Timeframe: Change from baseline VAS at 4 week
Ankle pain
Timeframe: Change from baseline VAS at 12 week