CompletedPhase 4

Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.

Norway68 participantsStarted 2019-09-03

Plain-language summary

The study objective is to examine if a high propofol dose is non-inferior to a low dose in respect to hemodynamic stability in healthy patients during induction of general anesthesia with propofol and remifentanil.

Who can participate

Age range18 Years – 50 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy women * Age 18-50 years * Gynecological procedures * General anesthesia Exclusion Criteria: * Pre-existing hypertension * Diabetes for several years * Ischemic heart disease * Cerebrovascular disease * Heart valve disease * Verified cardiac arrhythmia * Anaemia * Kidney or hepatic disease * Hypersensitivity for soya, eggs or peanuts * Pregnancy * Poor health state * Illicit substance use * BMI \<20 or \>35 kg/m2 * SBP \>150 mmHg * HR \>100 beats/min

What they're measuring

Systolic blood pressure (SBP)

Timeframe: The first 7.5 minutes during induction of general anesthesia

Heart rate (HR)

Timeframe: The first 7.5 minutes during induction of general anesthesia

Trial details

NCT IDNCT03861364

SponsorHelse Fonna

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-05-19

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