CompletedNot Applicable

Association Between Lactase Deficiency, and the Small Intestinal Microbiome in Adults.

United States37 participantsStarted 2018-11-21

Plain-language summary

The purpose of this study is to study the role of the enzyme (substance produced by the body that helps in a biochemical reaction like digestion in the body) responsible for digestion of lactose and the role of the gut bacteria (bacteria in the intestine) in producing symptoms of lactose intolerance.

Who can participate

Age range18 Years – 75 Years

SexALL

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Exclusion criteria

✕. Patients with known bleeding diathesis given the need for small intestinal mucosal biopsies.
✕. Patients with known history of eosinophilic esophagitis, inflammatory bowel disease, chronic pancreatitis or pancreatic insufficiency, celiac disease, peptic duodenitis
✕. Antibiotic-use within the last 30 days
✕. Major abdominal surgery except appendectomy or cholecystectomy \> 6 months prior to enrollment
✕. Prior radiation therapy of the abdomen
✕. Use of tobacco products within the last 3 months
✕. Allergy to milk
✕. Currently pregnant or breast-feeding

What they're measuring

Lactase activity

Timeframe: 1 day

Trial details

NCT IDNCT03860051

SponsorIndiana University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06-30

View on ClinicalTrials.gov More Lactose Intolerance trials