CompletedPhase 3

Erector Spinae Block Versus Surgeon Infiltration in VATS Procedures

United States120 participantsStarted 2019-02-07

Plain-language summary

The study is comparing the difference between erector spinae block and surgeon infiltration after VATS (Video Assisted Thoracoscopic Surgery). The outcomes measured are pain scores, opioid usage, opioid side effects, and patient satisfaction.We are also also studying the effectiveness of liposomal bupivacaine (EXPAREL) in a block by randomizing patients to both EXPAREL erector spinae block and simple bupivacaine erector spinae block.

Who can participate

Age range18 Years – 100 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pt undergoing VATS including but not limited to wedge or lobectomy at Indiana University Hospital * ASA 1,2,3 or 4 * Age 18 or older, male or female * Desires regional anesthesia for postoperative pain control Exclusion criteria: * Any contraindication for Erector Spinae Plane block * History of substance abuse in the past 6 months which would include heroin, marijuana or any other illegal street drugs * Patient staying intubated after surgery * Patient (home dose) taking more than 30mg PO morphine equivalent per day * Known allergy or other contraindications to the study medications, which include dilaudid and bupivacaine. * Pts. scheduled for a pleurodesis, decortication or esophagectomy at Indiana University Hospital

What they're measuring

The Primary Endpoint of This Study Will be 24 Hours VAS Pain Score at Rest

Timeframe: 24 hours pain score at rest

The Primary Endpoint of This Study Will be 24 Hours VAS Pain Score With Movement

Timeframe: 24 hours pain score with movement

The Primary Endpoint of This Study Will be 48 Hours VAS Pain Score at Rest

Timeframe: 48 hours pain score at rest

The Primary Endpoint of This Study Will be 48 Hours VAS Pain Score With Movement

Timeframe: 48 hours pain score with movement

Trial details

NCT IDNCT03859635

SponsorIndiana University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-11-06

Results submitted2024-03-19

View on ClinicalTrials.gov More Pain, Postoperative trials