Hypofractionated Palliative Radiotherapy in Patients With Advanced Non-operable Rectal Cancer (NCT03853733) | Clinical Trial Compass
RecruitingNot Applicable
Hypofractionated Palliative Radiotherapy in Patients With Advanced Non-operable Rectal Cancer
Spain50 participantsStarted 2016-10-01
Plain-language summary
Many patients with rectal cancer were not candidates for surgical resection because advanced age, comorbidities, or multiple synchronous metastases. In this scenario only comfort measures or different palliative radiotherapy regimens are applied, from single doses to treatments lasting several weeks. The aim of this prospective study is to describe the preliminary results of our protocol of hypofractionated palliative radiotherapy in patients with non-operable rectal cancer.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Patients with rectal or sigmoidal cancer who were not candidates for surgical resection because advanced age, comorbidities, or multiple synchronous metastases at the time of diagnosis
. Patients with = or \> 18 years old
. Patients treated with a radiotherapy dose of 39Gy in 13 fractions of 3 Gy
Exclusion criteria
. Patients with a non rectum or sigma colo-rectal cancer.
. Patients with \<18 years old.
. Patients treated with concurrent chemotherapy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Symptomatic response after palliative radiotherapy (bleeding)
Timeframe: two months afer the end of radiotherapy
2
Symptomatic response after palliative radiotherapy (pain)
Timeframe: two months afer the end of radiotherapy
3
Gastrointestinal toxicity after the end of radiotherapy
Timeframe: two months afer the end of radiotherapy
4
Genitourinary toxicity after the end of radiotherapy
Timeframe: two months afer the end of radiotherapy