CompletedNot Applicable

Prehabilitation of Frail Surgical Cancer Patients Using Remote Ischemic Preconditioning

United States17 participantsStarted 2019-02-22

Plain-language summary

This project will examine the efficacy of a simple, cost-effective, non-invasive intervention, called remote ischemic preconditioning (RIPC), to reduce frailty in pre-surgical, frail, elderly patients with colon cancer. The investigators hypothesize that RIPC will reduce frailty in the pre-surgical period (as assessed by distance walked during the 6-minute walk test), improve functional capacity 4-weeks postoperatively, and reduce intraoperative blood pressure variability. If successful, future studies will examine the efficacy of RIPC to improve surgical outcomes in frail cancer patients.

Who can participate

Age range55 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Be between the ages of 55-85 * Have a positive diagnosis of colon cancer or suspected colon cancer based on pathology report * Be scheduled for curative resection of non-metastatic colon cancer * Have a 6-Minute Walk Test distance ≤80% of predicted value based on age and sex. Exclusion Criteria: * Condition which prevents walking * Any condition in which compression of the arm or transient ischemia is contraindicated (e.g. wounds in the arm) * Neurodegenerative disorder * Unstable angina in previous month * Myocardial infarction during previous month.

What they're measuring

6 Minute Walk Test Distance (Pre Surgery)

Timeframe: Pre-Surgery

Trial details

NCT IDNCT03853473

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-02-01

Results submitted2024-05-22

View on ClinicalTrials.gov More Colon Cancer trials