CompletedPhase 1

Minimally Invasive Sensing of Beta-lactam Antibiotics

United Kingdom11 participantsStarted 2018-04-12

Plain-language summary

This study is an in-house feasibility study of a microneedle biosensor developed within Imperial College London.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult \>18 years old * Healthy with no evidence of active infection * Previously received penicillin with no adverse effects Exclusion Criteria: * High risk of skin soft tissue infection or local skin and soft tissue infection near sensor site * Previous history of allergies to adhesive strips or active dermatitis * Penicillin allergy or previous adverse event whilst receiving penicillin * Anaemia on screening bloods (defined as haemoglobin \<13 g/dL in males and \<12 g/dL in females)

What they're measuring

Assessment of the Biosensors Ability to Track Phenoxymethylpenicillin Concentrations Compared to Observations Made by Microdialysis and Blood Sampling

Timeframe: Up to 12 hours

Trial details

NCT IDNCT03847610

SponsorImperial College London

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-08-10

Results submitted2020-11-06

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