CompletedPhase 4

Double Pick up in Poor Prognosis Women

Belgium48 participantsStarted 2019-10-01

Plain-language summary

The purpose of this randomized pilot study is to compare the efficacy of double oocyte retrieval vs. conventional antagonist ovarian stimulation protocol in poor prognosis patients undergoing in vitro fertilization (IVF) or intra-cytoplasmic sperm injection (ICSI).

Who can participate

Age range25 Years – 40 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 25-40 years * Body mass index (BMI) ≤ 35 and ≥ 19 * Antimüllerian hormone (AMH) level of ≤1.5 ng/mL or antral follicular count (AFC) of ≤6 follicles or ≤5 oocytes retrieved in a previous cycle following standard conventional ovarian stimulation. Exclusion Criteria: * Testicular sperm extraction * History of \> 3 three consecutive previous unsuccessful IVF cycles * BMI \>35 or \<19 * Use of oral contraceptives \<3 months before start of the treatment * polycystic ovary syndrome (PCOS) according to the Rotterdam criteria * Ovarian stimulation for pre-implantation genetic testing (PGT-A/M) * Medical/social freezing * In vitro maturation (IVM) * History of untreated autoimmune, endocrine or metabolic disorders, * Ovarian cystectomy or oophorectomy

What they're measuring

Number of MII Oocytes Retrieved Between the Two Arms

Timeframe: 1 month

Trial details

NCT IDNCT03846544

SponsorCRG UZ Brussel

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-09-15

Results submitted2023-10-23

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