RESCUE-RACER is jointly sponsored by the University of Cambridge and Cambridge University Hospitals NHS Foundation Trust. The RESCUE-RACER programme evaluates motorsports competitors at baseline (CArBON) and post-injury (CARS). The CArBON study (Competitor Assessment at Baseline; Ocular, Neuroscientific) collects a battery of neuroscientific data in a baseline assessment. The CARS study (Concussion Assessment and Return to motorSport), repeats the CArBON battery throughout the recovery period in competitors who sustain a potentially concussive event during motorsport. The primary outcome of the RESCUE-RACER programme is to establish the natural history of concussive symptoms and signs in motorsport competitors using a comprehensive neuroscientific battery. The standard clinical assessment of concussive symptoms will be correlated with objective clinical scoring, in addition to neurocognitive and neuropsychological assessments. Advanced brain imaging with MRI will be used to further characterize head injuries in motorsport. Finally, salivary biomarkers will be collected to monitor the measurable biological effects of a potentially concussive event immediately following injury and through recuperation in the recovery period. The secondary outcome is investigation of a novel diagnostic tool for concussion, in the form of a 3D head-mounted display and eye tracking system capable of assessing ocular, vestibular and reaction time (OVRT) functions (the I-PAS device, now re-named Dx 100). The results of RESCUE-RACER will form an evidence base for medical decision-making track side after a potentially-concussive incident and will advise on clinic management of motorsports concussion, including the important 'return-to-race' decision.
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Change in SCAT5 decision scores
Timeframe: Baseline (CArBON assessments) to 1-3 weeks after concussion (CARS assessments)
Change in computerised neurocognitive assessment scores
Timeframe: Baseline (CArBON assessment) to 1-3 weeks after concussion (CARS assessments)
Change in computerised neuropsychological assessment scores
Timeframe: Baseline (CArBON assessment) to 1-3 weeks after concussion (CARS assessments)
Change in the brain's microstructural architecture, or functional changes in the brain
Timeframe: Baseline (CArBON assessment) to 1-3 weeks after concussion (CARS assessments)
Change in salivary biomarker levels
Timeframe: Baseline (CArBON assessments) to 1-3 weeks after concussion (CARS assessments)