Involvement of Immune Cells Derived From the Intestine in Sjogren's Syndrome (NCT03841318) | Clinical Trial Compass
CompletedNot Applicable
Involvement of Immune Cells Derived From the Intestine in Sjogren's Syndrome
France57 participantsStarted 2020-08-03
Plain-language summary
The study aims at defining the role of immune cells derived from the intestine in the pathogenesis of Sjogren's disease. This research might open new therapeutic approaches for the treatment of autoimmune diseases.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Suspicion of Sjogren's syndrome based on 2016 American College of Rheumatology (ACR) criteria;
* Age ≥ 18 years
* Being affiliated to health insurance
* Willing to participate
Exclusion Criteria:
* Pregnant or breastfeeding women,
* Patient concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial studied immune cells found in the salivary glands of people with Sjögren's syndrome — has my doctor seen the results, and do they change anything about how my condition might be assessed or treated?
2Since this was a completed study focused on understanding the role of gut-derived immune cells in Sjögren's syndrome, could my doctor explain what that kind of research might eventually mean for new treatments or diagnostic approaches?
3This trial involved collecting minor salivary gland tissue for analysis — is a minor salivary gland biopsy something that might be relevant or recommended in my own care, and what would that involve?
4Because this was a research study aimed at better understanding the biology of Sjögren's syndrome rather than testing a new treatment, should I be looking at other active trials that are testing actual therapies, and if so, which might be worth considering for my situation?
5Given that this study looked at immune cell infiltration in salivary glands, could my doctor help me understand how that kind of immune activity relates to the specific symptoms I'm experiencing, and whether it might guide any decisions about my treatment plan?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Quantification of the immune cells infiltrated in the minor salivary glands of Sjogren's patients.