Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infections

Inclusion Criteria: * Adult male and female * Documented diagnosis of pyuria * Documented diagnosis of cUTI or Acute Pyelonephritis (AP) Exclusion Criteria: * Receipt of effective antibacterial drug therapy for cUTI for more than 24 hours during the previous 72 hours prior to randomization * A urine culture result is resistant to meropenem or a gram negative pathogen is not identified or more than 2 microorganisms are isolated or a confirmed fungal UTI is identified * Required use of nonstudy systemic bacterial therapy * Suspected or confirmed prostatitis or urinary tract symptoms attributable to sexually transmitted disease * Patients with perinephric or renal abscess * Patients with renal transplantation or receiving hemodialysis or peritoneal dialysis * Abnormal labs