Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHop (NCT03835741) | Clinical Trial Compass
TerminatedNot Applicable
Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHop
Stopped: The clinical implementation of the system used in the study as well as its routine use limited the possibilities of carrying out this project.
Canada17 participantsStarted 2018-12-17
Plain-language summary
The aim of this study is to evaluate if automated adjustment of oxygen (with FreeO2 device) can reduce the hospital length of stay for acute exacerbation of COPD with comparison of manual oxygen titration.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* COPD or suspected COPD ( Age\>40, active or smoking history \> 10pack/years), -
* Acute exacerbation (increasing dyspnea recently)
* One or more of the following criteria: increased sputum, modification of sputum purulence,increased dyspnea,
* Moderate oxygen therapy: Oxygen flow \< 8 lpm (or FiO2 \< 0.60) to maintain a SpO2 \>or = 92% (for long term oxygen therapy, the oxygen flow must be greater than baseline flow to maintain SpO2 \> or = 92%)
Exclusion Criteria:
* Patient refusal
* COPD exacerbation with diagnosis highly related to pulmonary embolism, cardiac pulmonary edema, pneumothorax or sedative overdose
* No SpO2 signal
* Encephalopathy score \> 2
* Delirium
* Other respiratory support needed (intubation or NIV)
* Patient on withdrawal life support
* Advance neoplasia (palliative stage) or terminal respiratory distress
* Unavailability of FreeO2 device at the randomisation
* Non optimal patient collaboration
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Hospital length of stay
Timeframe: From hospital admission until hospital discharge (around one week expected)