TerminatedNot Applicable

Oesophagectomy and Chest Wall and Respiratory Function

Stopped: Study closed before the planned recruitment target was reached because the study period ended before full recruitment could be completed. Recruitment ceased at study closure and data collection was completed for enrolled participants.

United Kingdom73 participantsStarted 2019-05-29

Plain-language summary

Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%). Minimally invasive approach through keyhole surgery has been shown to reduce pulmonary infections by 20%. Enhanced recovery programmes are evidence-based protocols, developed to achieve early recovery after surgery with early mobilisation and chest physiotherapy and have been shown to reduce pulmonary complication rates as well. The investigators intend to objectively measure chest wall movement using 3D motion capture system as well as a wearable measurement system to monitor chest wall movement.

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients treated more than a year ago with oesophagectomy for oesophageal cancer, by an open approach.
. Patients able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study.
. Healthy volunteers with no underlying respiratory disease and no history of upper gastrointestinal surgery.
. Individuals able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Chest wall movement

Timeframe: Each participant will undergone one assessment during the study. The whole session, all procedures included, will last approximately 60 minutes.

Lung function

Timeframe: Each participant will undergone one assessment during the study. The whole session, all procedures included, will last approximately 60 minutes.

Trial details

NCT IDNCT03835273

SponsorImperial College London

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-08-31

View on ClinicalTrials.gov More Esophageal Cancer trials

Plain-language summary

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients treated more than a year ago with oesophagectomy for oesophageal cancer, by an open approach.
. Patients able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study.
. Healthy volunteers with no underlying respiratory disease and no history of upper gastrointestinal surgery.
. Individuals able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study.

What they're measuring

Chest wall movement

Timeframe: Each participant will undergone one assessment during the study. The whole session, all procedures included, will last approximately 60 minutes.

Lung function

Timeframe: Each participant will undergone one assessment during the study. The whole session, all procedures included, will last approximately 60 minutes.