RecruitingNot Applicable

Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder

United States100 participantsStarted 2019-03-27

Plain-language summary

The purpose of this study is to use eye-tracking technology to study attentional biases, reward sensitivity, and cognitive control in adult patients with bipolar disorder with or without anxiety and/or substance use disorder comorbidity.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

✕. Inclusion Criteria for Group 1:
✕. Inclusion and Exclusion Criteria for Group 2: Bipolar disorder with a current anxiety disorder (generalized anxiety disorder, panic disorder, and/or social phobia)
✕. Inclusion and Exclusion Criteria for Group 3: Bipolar disorder with a current anxiety disorder and a current substance use disorder
✕. Inclusion and Exclusion Criteria for Group 4: Bipolar disorder without an anxiety disorder but with a current substance use disorder
✕. Inclusion and exclusion criteria for Group 5: Healthy Volunteers
✕. Inclusion criteria for Group 5:

What they're measuring

Measure the differences in attentional bias among the 5 groups by assessing how long it takes a subject to locate and fixate on each face on the screen

Timeframe: Baseline

Measure the differences in reward sensitivity among the 5 groups by assessing the amplitude of the saccade to reward and non-reward stimuli

Timeframe: Baseline

Measure the differences in reward sensitivity among the 5 groups by assessing the velocity of the saccade to reward and non-reward stimuli

Timeframe: Baseline

Measure the differences in cognitive control among the 5 groups by assessing the amplitude of the antisaccade

Timeframe: Baseline

Measure the differences in cognitive control among the 5 groups by assessing the velocity of the antisaccade

Timeframe: Baseline

Trial details

NCT IDNCT03829787

SponsorUniversity Hospitals Cleveland Medical Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-09-01

Contact for this trial

Nicole Jones

216/844-2862 mdp@uhhospitals.org

View on ClinicalTrials.gov More Bipolar Disorder trials

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

✕. Inclusion Criteria for Group 1:
✕. Inclusion and Exclusion Criteria for Group 2: Bipolar disorder with a current anxiety disorder (generalized anxiety disorder, panic disorder, and/or social phobia)
✕. Inclusion and Exclusion Criteria for Group 3: Bipolar disorder with a current anxiety disorder and a current substance use disorder
✕. Inclusion and Exclusion Criteria for Group 4: Bipolar disorder without an anxiety disorder but with a current substance use disorder
✕. Inclusion and exclusion criteria for Group 5: Healthy Volunteers
✕. Inclusion criteria for Group 5:

What they're measuring

Measure the differences in attentional bias among the 5 groups by assessing how long it takes a subject to locate and fixate on each face on the screen

Timeframe: Baseline

Measure the differences in reward sensitivity among the 5 groups by assessing the amplitude of the saccade to reward and non-reward stimuli

Timeframe: Baseline

Measure the differences in reward sensitivity among the 5 groups by assessing the velocity of the saccade to reward and non-reward stimuli

Timeframe: Baseline

Measure the differences in cognitive control among the 5 groups by assessing the amplitude of the antisaccade

Timeframe: Baseline

Measure the differences in cognitive control among the 5 groups by assessing the velocity of the antisaccade

Timeframe: Baseline