CompletedNot Applicable

Immediate ART in Subjects With Opportunistic Diseases

Mexico114 participantsStarted 2019-02-18

Plain-language summary

The aim of this study is to compare the clinical response and mortality rate by an opportunistic disease in HIV-infected individuals who start immediate versus conventional antiretroviral therapy. Immediate ART (iART) is defined as starting antiretroviral therapy in the first 48 hours after the hospitalization. Conventional ART (cART) is defined as starting antiretroviral therapy once the opportunistic infection is under control at the discretion of infectious disease specialist.

Who can participate

Age range18 Years – 60 Years

SexALL

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Inclusion Criteria: * Over 18 years old * Time from admission to study entry: less than 48 hours * Confirmed HIV diagnosis or high probability of HIV infection based on a positive HIV rapid test * Having an opportunistic disease * Subjects must be naïve to ART or have failed their first or second ART regimen or must have abandoned ART for more than 3 months Exclusion Criteria: * Meningitis due to Cryptococcus spp. or for M. tuberculosis * Pregnancy

What they're measuring

Mortality

Timeframe: 30 days

Trial details

NCT IDNCT03825523

SponsorGustavo Reyes-Teran

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2025-08-05

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