Genetic diagnosis for neonates suffering from epilepsy has important implications for treatment, prognosis, and development of precision medicine strategies. Investigator performed exome sequencing (ES) or targeted sequencing on neonates with seizure onset within the first month of life. Investigator subgrouped our patients based on the onset age of seizure into neonatal and before 1 year (1-12 months), to compare the clinical and genetic features and treatment strategies.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Mutation rate of common seizure genes
Timeframe: From the oneset of seizure to the genetic sequencing finish, the process may last up to 3 months.
Rate of seizure free
Timeframe: From the onset of seizure to 6 months after the onset of seizure