Impact of Art Therapy on Brain Connectivity in Recent Post-Stroke Aphasia (NCT03820843) | Clinical Trial Compass
CompletedNot Applicable
Impact of Art Therapy on Brain Connectivity in Recent Post-Stroke Aphasia
France15 participantsStarted 2020-02-17
Plain-language summary
A stroke located in the left parieto-temporal junction is associated, in aphasic right-handed patients, with a poor prognosis for language recovery. The role of the right hemisphere in recovering post-stroke aphasia is still controversial. Our hypothesis, based on recent work in imaging, is that early activation of the right hemisphere linked to the practice of the visual arts could facilitate language recovery in extended posterior left strokes that completely disrupt language areas.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with recent ischemic or haemorrhagic stroke with unilateral lesion (s) of the parieto-temporal left junction present on the Diffusion MRI (DWI) performed in acute phase at 24-48h
* Post stroke delay of 15 days to 2 months
* Existence of moderate to severe phasic disorders on Aphasia Rapid Test score (ART, score\> 6, scale of 26 items)
* Patient able to read and understand French
* Rightful
* Normal and corrected vision and hearing
* Absence of pre-existing degenerative neurological disorder
* Patient having signed his consent
* Age ≥ 18 years
Exclusion Criteria:
* Patients with contraindications to MRI or claustrophobic
* Patients under legal protection
* Patients with behavioral disorders or disabling neurovisual disorders making participation in art therapy impossible
* Mute patients, illiterate patients
* Patients leaving the neurological SSR department prematurely
* Patients not affiliated to a social security scheme
* Pregnant or lactating women.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
change from baseline measurement of white substance bundles volumes for structural connectivity at 6 weeks
Timeframe: from inclusion at 6 weeks
2
change from baseline measurement of synchrony amplitude of slow fluctuations for functional Connectivity at 6 weeks