CompletedNot Applicable

Metabolomics Study on Intensive Care Acquired Muscle Weakness in Polytrauma

Germany10 participantsStarted 2019-03-24

Plain-language summary

In this mono-center pilot trial, polytrauma patients admitted to intensive care will be included. Investigators are going to take blood and muscle samples at respecified time points to do metabolic, histological and molecular testing. Aim of the study is to investigate (1) changes of the blood metabolome in patients with ICUAW (intensive care unit acquired weakness) and (2) identify metabolic components who are responsible for ICUAW or can be used as marker for ICUAW.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * acute polytrauma patient * age ≥ 18 years old * expected intensive care stay ≥ 3 days * American Society of Anesthesiologists classification I or II Exclusion Criteria: * patient had received cardiopulmonary resuscitation * limitation of therapy or comfort care

What they're measuring

Metabolomics

Timeframe: a median of 14 days

Trial details

NCT IDNCT03819959

SponsorTechnical University of Munich

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-04-22

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