CompletedNot Applicable

Clinical Comparative Analysis of Bretschneider and St. Thomas Cardioplegia Solution in Case of Mitral Valve Repair Via Anterolateral Right Thoracotomy

Switzerland200 participantsStarted 2019-04-01

Plain-language summary

Mitral valve reconstruction via minimal invasive antero- lateral thoracotomy is done in cardioplegia with a cardioplegic solution, either HTK-Bretschneider (Custidiol®) (a crystalloid intracellular solution) or St. Thomas (a crystalloid extracellular solution). This study investigates HTK-Bretschneider versus St. Thomas cardioplegic solution regarding peri- and postoperative outcome, especially for cardiac biomarkers.

Who can participate

SexALL

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Inclusion Criteria: * Mitral valve reconstruction via minimal invasive antero- lateral thoracotomy done in cardioplegia with a cardioplegic solution, either HTK-Bretschneider (Custidiol®) (a crystalloid intracellular solution) or St. Thomas (a crystalloid extracellular solution). Exclusion Criteria: * Mitral valve reconstruction via minimal invasive antero- lateral thoracotomy done in cardioplegia with cardioplegic Solutions other than HTK-Bretschneider (Custidiol®) (a crystalloid intracellular solution) or St. Thomas (a crystalloid extracellular solution).

What they're measuring

high specific troponin T (hs-TrT) (μg/l)

Timeframe: perioperative during minimal invasive surgery

Creatin-Phosphokinase (CK) (U/l)

Timeframe: perioperative during minimal invasive surgery

Creatinkinase Muscle- Brain (CK-MB) (U/l)

Timeframe: perioperative during minimal invasive surgery

Trial details

NCT IDNCT03818113

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-08-30

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