CompletedPhase 4

Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.

Pakistan116 participantsStarted 2019-06-25

Plain-language summary

The aim of the study is to investigate the analgesic effects of the subcutaneous wound infiltration with tramadol, ketamine, dexamethasone, dexmedetomidine and midazolam as adjuvant to ropivacaine, compared to ropivacaine alone in patients undergoing Video-Assisted thoracoscopic Surgery (VATS) procedures.

Who can participate

Age range18 Years – 65 Years

SexALL

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Inclusion criteria

✓. ASA I to III.
✓. Age \>18 years.
✓. Either sex.
✓. Elective Video assisted thoracotomy surgery (VATS) under general anaesthesia

Exclusion criteria

✕. ASA IV \& V.
✕. Coagulation disorders.
✕. Infection at the vicinity of the surgical wound.
✕. Raised intracranial pressure.
✕. History of hypersensitivity or known allergy to any study drug.
✕. History of opioid addiction.
✕. History of seizure disorder.
✕. Those who are not willing to participate in the study.

What they're measuring

Time to the first postoperative analgesia requirement

Timeframe: Follow till 24 hours postoperatively

Visual analogue scale (VAS)

Timeframe: Follow till 24 hours postoperatively

Trial details

NCT IDNCT03809442

SponsorAga Khan University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-08-31

View on ClinicalTrials.gov More Postoperative Analgesia trials