CompletedPhase 4

Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant Schizophrenia

India60 participantsStarted 2019-02-01

Plain-language summary

The proposed study will be conducted to compare the efficacy of maintenance ECT (M-ECT) vs Clozapine in treatment resistant schizophrenia (TRS) in terms of change in psychopathology measures and cerebral hemodynamics.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients clinically diagnosed with treatment-resistant schizophrenia (TRS) (TRRIP consensus criteria). * Patients aged 18-60 years of either sex. * Patients giving voluntary written consent for participation in the study Exclusion Criteria: * Patient already on Clozapine or ECT. * History of psychoactive substance abuse or dependence. * Co-morbid psychiatric, major medical, or neurological disorders. * History of organicity or significant head injury. * Pacemaker or metal in any part of the body excluding the mouth. * Pregnant and breastfeeding females.

What they're measuring

Change in severity of psychopathology

Timeframe: 24 weeks

Trial details

NCT IDNCT03807882

SponsorAll India Institute of Medical Sciences, Bhubaneswar

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-05-31

View on ClinicalTrials.gov More Treatment Resistant Schizophrenia trials