UnknownNot Applicable

Study of Accurate Diagnosis and Treatment of Peutz-Jeghers Syndrome

China150 participantsStarted 2018-03-01

Plain-language summary

The mutation of STK11 has been regcognized to be the major cause of Peutz-Jeghers syndrome (PJS).The aim of this study was to confirm the mutation rate of gene associated with gastrointestinal malignancies,including STK11, APC,PMS1,et al. Furtherly, the investigators analyze the association of STK11 with gut microbiota.

Who can participate

Age range5 Years – 70 Years

SexALL

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Inclusion criteria

✓. Subject with ages from 18-70 years old.
✓. Subject diagnosed with Peutz-Jeughers syndrome.
✓. Subject without hypertension, diabetes and other gastrointestinal diseases.
✓. The consent form has been signed.

Exclusion criteria

✕. Subject is younger than 18 years or older than 70 years.
✕. Subject with hypertension,diabetes and other gastrointestinal diseases.
✕. Subject taken or adminstered medicine associated with digestive function during latest 1 month.
✕. Pregnant women.

What they're measuring

Mutation of gene associated with Peutz-Jeghers syndrome

Timeframe: 2 years

Trial details

NCT IDNCT03806075

SponsorYiqi Du

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-09-01

Contact for this trial

Yuxin Wang, Ph.D.

86-18721819083 18721819083@163.com

View on ClinicalTrials.gov More Peutz-Jeghers Syndrome trials