CompletedNot Applicable

Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response

Colombia20 participantsStarted 2013-07-02

Plain-language summary

This study measures SP, CGRP and VEGF expression in human dental pulp under occlusal trauma induced by occlusal interferences under moderate orthodontic forces or under a combination of occlusal trauma and moderate orthodontic forces because in clinical reality, patients under orthodontic treatment experience a combination of these stimuli on their pulp tissue.

Who can participate

Age range18 Years – 30 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Teeth in normal masticatory function * Complete root development verified clinically and radiographically Exclusion Criteria: * Patients under medication * Smokers * Pregnant women were excluded * Teeth with caries * Teeth with restaurations, * Teeth with previous orthodontic treatment * Teeth with periodontal disorders * Teeth with parafunctional habits.

What they're measuring

SP expression (pmol/mg in pulp tissue)

Timeframe: 24 hours stimulations

Trial details

NCT IDNCT03804034

SponsorInstitucion Universitaria Colegios de Colombia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-01-27

View on ClinicalTrials.gov More Occlusal Trauma trials