Active — Not RecruitingNot Applicable

Optimal Treatment Protocol for Selective Laser Trabeculoplasty

Sweden400 participantsStarted 2019-01-10

Plain-language summary

A randomized controlled trial to evaluate which treatment protocol in selective laser trabeculoplasty that is most optimal in terms of efficacy and safety.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * diagnosis primary open-angle glaucoma, pseudo-exfoliative glaucoma or ocular hypertension. * intra-ocular pressure (IOP) at least 18 mmHg treatment day. * treatment is performed by an experienced laser surgeon. * SLT treatment and follow-up are expected to be possible to perform in an adequate way, considering anatomical factors, age and the general health of the patient. Exclusion Criteria: * change of IOP-lowering medication during the last three months. * planned change of intra-ocular-pressure-lowering medication. * previous glaucoma surgery (other than SLT and ALT) * previous intra-ocular surgery during the last three months. * previous intra-ocular inflammatory disease during the last year. * planned intra-ocular surgery. * hyper-pigmented anterior chamber angle.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in intraocular pressure (IOP)

Timeframe: Before SLT and thereafter regularly for 3 years

Achievement of 20% reduction in IOP

Timeframe: For 3 years

Survival (no additional intervention)

Timeframe: For 3 years

Trial details

NCT IDNCT03798223

SponsorVastra Gotaland Region

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2027-12-31

View on ClinicalTrials.gov More Glaucoma, Open-Angle trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.