Biochemical Versus Ultrasound Findings as Predictors of Fetal Loss in Cases of First Trimester Threatened Miscarriage

Inclusion Criteria: * Singleton Pregnancy. * Age20-35years. * Gestational age between6 to 8weeks. * Threatened miscarriage is diagnosed by vaginal bleeding, closed cervix and positive fetal life. * Patients who are sure of their dates (three regular menstrual cycles before conception without the use of hormonal contraception. Exclusion Criteria: Patients with recurrent miscarriage or pregnancy of unknown location (PUL). * Patients had ovulation induction medications or on progesterone treatment. * Patients with past medical history of diabetes mellitus or chronic hypertension. * Patients who are unsure of the last menstrual period date or with irregular menstrual cycle. * Pregnancy associated with presence of ovarian cyst. * Molar pregnancy. * Those who had a history of maternal disease which would cause an increase in CA-125level. These diseases include chronic pelvic infection, endometriosis, myoma uteri, endometrioma and lung, kidney and hepatic diseases.