Virtual Reality- Working Memory Retraining (NCT03786276) | Clinical Trial Compass
CompletedNot Applicable
Virtual Reality- Working Memory Retraining
United States30 participantsStarted 2019-02-01
Plain-language summary
This study will establish the acceptability and feasibility of enrolling and retaining heavy drinking Veterans with mild traumatic brain injury (mTBI) in an 8-week, randomized cross-over design trial of active VR working memory retraining (WMR). This study will also seek to establish the efficacy of active VR-WMR to increase performance in executive function.
Who can participate
Age range18 Years – 65 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* must report "heavy" drinking by NIH/NIAAA criteria (\>7 drinks/week for women; \>14 drinks/week for men) for at least one week in the last 90 days
* must meet moderate to severe criteria for current (past year) alcohol use disorder (AUD) by DSM-5
* must express a desire to reduce, stop, or maintain cessation of alcohol use
* must report a history of TBI as defined by American Congress of Rehabilitation Medicine (ACRM), in the chronic, stable phase of recovery (\>6 months from injury)
Exclusion Criteria:
* Unstable medical or psychiatric disorders judged to be unstable in the clinical judgment of the PI
* Current or past history of intrinsic cerebral tumors, HIV infection, cerebrovascular accident, aneurysm, arteriovenous malformations, myocardial infarction, cerebrovascular or peripheral vascular disease, type-1 diabetes, any cardiac, hepatic or renal diseases/disorders, surgical implantation of neurostimulators or cardiac pacemakers, medically diagnosed chronic obstructive pulmonary disease, demyelinating and neurodegenerative diseases, history of seizure disorder, and/or any physical disability making it impossible to use exercise equipment
* No female participant will be pregnant or attempting to conceive
* Concurrent participation in an AUD, cognitive training, or exercise study
* Must not require acute medical detoxification from alcohol (CIWA-AD \> 11) within the past week prior to study entry
* Subjects who, in the opinion of the investigator, …