EDRN Prostate MRI Biomarker Study

Inclusion Criteria: * Men with suspected but undiagnosed prostate cancer * To be scheduled/scheduled for biopsy as routine clinical care Exclusion Criteria: * Inability to obtain blood and urine per SOP or conduct an attentive DRE * Unable to undergo/tolerate a prostate MRI or failure to conduct the MRI * Prior diagnosis of prostate cancer * Prior prostate MRI unless being used as Index MRI (in this case index MRI can be one year prior to consent date) * Participating in clinical trial for prostate disease * Prior prostate surgery such as TURP, TUNA, TUMT, HOLEP, REZUM, UROlift * Prior PCA3, TMPRSS2:erg or MIPS panel performed for clinical purpose