CompletedNot Applicable

Effects of Preemptive Paracetamol and Ibuprofen on Headache and Myalgia in Patients After Electroconvulsive Therapy

Turkey (Türkiye)60 participantsStarted 2018-12-20

Plain-language summary

The primary aim this prospective, randomized, double-blind, placebo-controlled clinical trial is to compare the analgesic effects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia, and secondary aim is to evaluate the effects on hemodynamics, duration of seizure and postoperative side effects in patients who underwent electroconvulsive therapy .

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with major depression * Patients with American Society of Anesthesiologists (ASA) scores I or II * Between 18-65 Exclusion Criteria: * Patients with ASA scores III/IV, * Under the age of 18, * Over the age of 65, * Myocardial infarction, * Congestive heart failure, * Pulmonary disease, * Stroke history, * Bleeding disorder, * Hepatic and renal dysfunction, * Pregnant, * Migraine history, * Allergy of nonsteroidal anti-inflammatory drugs, paracetamol, propofol, * Neuromuscular disease, * Peptic ulcer disease, * Intracranial hypertension, * Glaucoma * Patients who did not give informed consent

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postoperative pain scores

Timeframe: From end of anesthesia (15 minutes after anesthesia) to after 24 hours, up to 24 hours

Trial details

NCT IDNCT03783312

SponsorInonu University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-02-07

View on ClinicalTrials.gov More Postoperative Pain trials