UnknownNot Applicable

Effect of Cervical Cerclage With Vaginal Progesterone in Asymptomatic Twin Pregnancies With a Sonographic Short Cervix

Egypt300 participantsStarted 2019-01-01

Plain-language summary

The objective of the present study is to evaluate the effectiveness of vaginal progesterone and cervical cerclage each alone and in combination in improving gestational age in twin pregnancy and its subsequent impact on perinatal outcome.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women pregnant in dichorionic twins. * Transvaginal sonographic cervical length is \<25 mm at 16-20 weeks gestational age. * No symptoms, signs or other risk factors for preterm labor Exclusion Criteria: * Age \< 18 years or \> 45 years. * Known allergy or contraindication (relative or absolute) to progesterone therapy. * Monochorionic twins. * Known major fetal structural or chromosomal abnormality. * Intrauterine death of one fetus or death of both fetuses. * Fetal reduction in the current pregnancy. * Medical conditions that may lead to preterm delivery. * Rupture of membranes. * Vaginal bleeding

What they're measuring

Preterm labor before 34 weeks

Timeframe: Up to 34 weeks gestational age

Trial details

NCT IDNCT03781466

SponsorAswan University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-12-31

Contact for this trial

hany f sallam, md

01022336052 hany.farouk@aswu.edu.eg

View on ClinicalTrials.gov More Twin; Pregnancy, Affecting Fetus or Newborn trials