Endometriosis on the bowel is a benign condition that can cause major complaints and severely affect the quality of life of women of fertile age. If medical treatment is not enough to improve pain and/or other symptoms it may be necessary to undergo major surgical treatment and removal of the endometriosis nodule on the bowel. Such extensive surgical treatment carries risks of serious complications. Therefore, a thorough diagnostic work-up before surgery is important to know the extent of disease. This will provide women with the best possible information and for the surgeon to plan the operation. The risk of complications increases as the bowel endometriosis is localized closer to the anus as well and/or if the bowel nodule is large. The distance between the anus and the nodule and the size of the nodule can be measured with two dimensional (2D) vaginal ultrasound. Additionally, Magnetic resonance imaging (MRI) is also used in some countries for these same measurements. Our study would like to investigate the diagnostic value of 2D ultrasound and MRI as well as learn more about women's quality of life before and after surgery. The investigators have designed the study to evaluate the following three questions into three studies ENDO1, ENDO2 and ENDO3: * ENDO1: How good is 2D transvaginal ultrasound at measuring the size of the bowel endometriosis nodule and the distance between anus and the lower part of the bowel nodule compared to measurements done during surgery? * ENDO2: What is the quality of life, sexual and bowel function of women before and 3- and 12-months after surgery due to bowel endometriosis? Questionnaires will be used. * ENDO3: How good is 2D transvaginal ultrasound at measuring the size of the bowel endometriosis nodule compared to magnetic resonance imaging (MRI) and measurements done during surgery?
Age range
18 Years – 50 Years
Sex
FEMALE
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
ENDO1AMeasurements on the distance between the lower margin of the rectal lesion and anal verge with 2D-TVS
Timeframe: Before scheduled surgery
ENDO1A: Measurements on the distance between the lower margin of the rectal lesion and anal verge
Timeframe: During scheduled surgery
ENDO1B: Size of bowel lesion measured on the excised bowel lesion.
Timeframe: During surgery.
ENDO1B: Size of bowel lesion measured with 2D-TVS.
Timeframe: Before scheduled surgery.
ENDO2: Incidence of low anterior resection syndrome (LARS)
Timeframe: Preoperatively, 3- and 12-months postoperatively
ENDO3: Correlation between Lesion to anal verge distance (LAVD) measured with 2D-TVS, MRI and measurements during surgery
Timeframe: Pre-operatively and during surgery
ENDO3: Measurements of bowel lesion size with MRI compared to 2D TVS and surgery
Timeframe: Before and during scheduled surgery