CompletedPhase 4

Repeatability in Hyperpolarized 3-Helium With MRI

United States18 participantsStarted 2008-07-22

Plain-language summary

The main purpose of this study is to assess and test the reproducibility and results of hyperpolarized 3-Helium gas as a contrast agent with Magnetic Resonance Imaging (MRI) of the lungs in healthy adult subjects.

Who can participate

Age range18 Years – 90 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * must be between the ages of 18 and 90 * must have a Body Mass Index (BMI) of \< 32 and weigh \< 200 lbs. Exclusion Criteria: * if female, must not be pregnant or breastfeeding * must not have any metal objects in or on their body including body piercings that cannot be easily removed, bullets, metallic fragments or slivers in eyes, skin, etc., pacemaker or defibrillation, aneurysm clips, cochlear implants, coronary stents, or neurostimulation. * must not have a history of claustrophobia, panic disorders, anxiety attacks, atrial fibrillation, uncontrolled high blood pressure, frequent ventricular ectopic rhythm, hemodynamic instability, kidney dysfunction or heart disease.

What they're measuring

Apparent Diffusion Coefficient (ADC) as a Function of Lung Inflation Levels.

Timeframe: Through study completion, measurements completed at one day visit only.

Trial details

NCT IDNCT03776747

SponsorEric A. Hoffman

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-06

Results submitted2022-12-06

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