CompletedNot Applicable

Glioma and Exercising

Switzerland39 participantsStarted 2018-10-26

Plain-language summary

To investigate the influence of two physical activity and exercising (PAE) interventions, namely resistance training and endurance training in relation to quality of life, depression, fatigue, sleep, anxiety, stress and coping, body image, and social interactions (psychological dimensions); cardiorespiratory fitness, morning cortisol secretion, inflammatory markers, and objective sleep (physiological dimensions), along with cancer-related dimensions

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with high grade glioma (WHO III° and IV°), and undergoing radiotherapy, chemotherapy, or both * Willing and able to follow the study intervention * Signed written informed consent Exclusion Criteria: * Severe psychiatric (psychosis, suicidal behavior, substance use disorder) and somatic comorbidities (severe cardiovascular disease, severe diabetes, impairments of the musculo-skeletal system) * patients not willing or able anymore to follow the study protocol.

What they're measuring

Change in Functional Assessment of Cancer Therapy Scale (FACT)

Timeframe: Baseline and week 3 and week 6

Change in Hamilton Depression Rating Scale (HDRS)

Timeframe: Baseline and week 3 and week 6

Change in Intolerance of Uncertainty Scale (IU)

Timeframe: Baseline and week 3 and week 6

Change in Insomnia Severity Index (ISI)

Timeframe: Baseline and week 3 and week 6

Change in Perceived Stress Scale (PSS)

Timeframe: Baseline and week 3 and week 6

Change in Fatigue Severity Scale

Timeframe: Baseline and week 3 and week 6

Change in Mental Toughness Questionnaire (MTQ48)

Timeframe: Baseline and week 3 and week 6

Change in International Physical Activity Questionnaire

Timeframe: Baseline and week 3 and week 6

Trial details

NCT IDNCT03775369

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-02-28

View on ClinicalTrials.gov More High Grade Glioma trials

Plain-language summary

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in Functional Assessment of Cancer Therapy Scale (FACT)

Timeframe: Baseline and week 3 and week 6

Change in Hamilton Depression Rating Scale (HDRS)

Timeframe: Baseline and week 3 and week 6

Change in Intolerance of Uncertainty Scale (IU)

Timeframe: Baseline and week 3 and week 6

Change in Insomnia Severity Index (ISI)

Timeframe: Baseline and week 3 and week 6

Change in Perceived Stress Scale (PSS)

Timeframe: Baseline and week 3 and week 6

Change in Fatigue Severity Scale

Timeframe: Baseline and week 3 and week 6

Change in Mental Toughness Questionnaire (MTQ48)

Timeframe: Baseline and week 3 and week 6

Change in International Physical Activity Questionnaire

Timeframe: Baseline and week 3 and week 6