CompletedNot Applicable

Mechanism and Dosimetry Exploration in TES Magnetic Resonance Current Mapping Methods

United States123 participantsStarted 2019-01-03

Plain-language summary

In this study the investigators will explore dosimetry in transcranial electrical stimulation using a novel magnetic resonance imaging technique that can determine how electrical stimulation distributes within the brain. The investigators will then combine this imaging technique with functional MR imaging to attempt mechanistic associations. If successful, the study outcomes will be an improved understanding of the interactions between electric current distributions and structures presumed to be targeted by stimulation.

Who can participate

Age range18 Years – 30 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * We will include neurologically normal volunteer subjects between 18-30 years of age in the study, minors will not be targeted. * English as Native Language Exclusion Criteria: * Adults who are unable to consent will not be included in the study. * Pregnancy * Subjects will not have any implanted or attached metallic devices. * Appreciable deficits in hearing * Appreciable problems with articulation * Neuroanatomic abnormality * Any neurological disorder associated with cognitive impairment. * Any implanted cardiac pacemaker * Dementia or Mini-Mental State Exam \<24 * Low estimated verbal intelligence per WTAR * Active or Prior history of Seizure Disorder * Family History of Seizure disorder * Prescribed Seizure inducing medication

What they're measuring

Replicability

Timeframe: 3 weeks

Comparison of measured current distribution with fMRI result

Timeframe: 2 weeks

Trial details

NCT IDNCT03772210

SponsorArizona State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-31