CompletedNot Applicable

Mechanism and Dosimetry Exploration in TES Magnetic Resonance Current Mapping Methods

United States123 participantsStarted 2019-01-03

Plain-language summary

In this study the investigators will explore dosimetry in transcranial electrical stimulation using a novel magnetic resonance imaging technique that can determine how electrical stimulation distributes within the brain. The investigators will then combine this imaging technique with functional MR imaging to attempt mechanistic associations. If successful, the study outcomes will be an improved understanding of the interactions between electric current distributions and structures presumed to be targeted by stimulation.

Who can participate

Age range

18 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * We will include neurologically normal volunteer subjects between 18-30 years of age in the study, minors will not be targeted. * English as Native Language Exclusion Criteria: * Adults who are unable to consent will not be included in the study. * Pregnancy * Subjects will not have any implanted or attached metallic devices. * Appreciable deficits in hearing * Appreciable problems with articulation * Neuroanatomic abnormality * Any neurological disorder associated with cognitive impairment. * Any implanted cardiac pacemaker * Dementia or Mini-Mental State Exam \<24 * Low estimated verbal intelligence per WTAR * Active or Prior history of Seizure Disorder * Family History of Seizure disorder * Prescribed Seizure inducing medication

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Replicability

Timeframe: 3 weeks

Comparison of measured current distribution with fMRI result

Timeframe: 2 weeks

Trial details

NCT IDNCT03772210

SponsorArizona State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-31

View on ClinicalTrials.gov More Transcranial Direct Current Stimulation trials